Seoochre

While the life sciences sector has incrementally adopted digital technologies over the years, the rate of digital transformation over the next five years looks to be unprecedented. Collaborations and acquisitions in the pursuit of digital transformation have accelerated significantly. In 2018, US$9.5 billion was invested in the digital health sector over 698 deals. From the FDA approval of Otsuka’s sensor embedded drug Abilify Mycite and the approval of Pear Therapeutics’ app for the treatment of opioid abuse, through to Takeda’s partnership with Emulate Inc for the use of organs on chips for

Artificial Intelligence (AI) and machine learning-based technologies have the potential to transform healthcare because they offer new and important insights derived from the vast amount of data generated during the delivery of healthcare every day. The capacity of AI to learn from real-world feedback and improve its performance makes this technology uniquely suited as Software as a Medical Device (SaMD) and is responsible for it being a rapidly expanding area of research and development. Clinical pharmacy practice may undergo major change due to the implementation of this technology. The cha

Controlling the industrial crystallisation process poses a significant obstacle in the production of drugs and numerous other products. Digitisation of the crystallisation process now allows for radical change by increasing process automation to control overall crystallisation. The main pillars of Pharma 4.0 are process automation, improved control strategies, data visualisation, cloud edge storage, chemometrics, and mathematical modelling technologies. SmartCrys is a revolutionary integrated process control system that harnesses the mainstays of Pharma 4.0 with the combination of PAT tools i

The cyber-physical security of any manufacturing system, specifically food and drug manufacturing, is essential. The technology in the pharmaceutical industry advanced significantly in last decade to improve upon every aspects of drug manufacturing. However, much less attention has been paid to identify and proactively mitigate the risk of cyber-physical attacks. Viruses that threaten these systems are very real and in recent years have proven very harmful and costly. Those that target drugs consumed by billions of people worldwide will inevitably have deadly consequences.

Data can be used to analyze genomes, prescribe pharmaceuticals in the pharmaceutical and biotechnology industries, and a variety of other applications. Now that data has become "BIG DATA," analyzing it has become a whole new field of "Analytics and Data Science." The cost of genome structure analysis has decreased from ten million dollars in 2007 to one thousand dollars thanks to analytics. On the basis of big data analysis, a cancer treatment was prescribed. It can be used in a variety of industries and enterprises. There are numerous firms that are solely dependent on analytics, as well as

While the life sciences sector has incrementally adopted digital technologies over the years, the rate of digital transformation over the next five years looks to be unprecedented. Collaborations and acquisitions in the pursuit of digital transformation have accelerated significantly. In 2018, US$9.5 billion was invested in the digital health sector over 698 deals. From the FDA approval of Otsuka’s sensor embedded drug Abilify Mycite and the approval of Pear Therapeutics’ app for the treatment of opioid abuse, through to Takeda’s partnership with Emulate Inc for the use of organs on chips for

Pharmacovigilance (PV) is increasingly taking its toll on life science organisations. According to EY research1, large pharmaceutical companies contend with an average of 700,000 adverse event (AE) cases each year, a number that IDC2 has found to be rapidly increasing by 30 to 50 per cent annually. The pandemic has exacerbated the situation, with the fast tracking of COVID-19 vaccines increasing AE caseloads to more than one million a year for some industry players. Companies are under pressure to manage this increased case load effectively while still maintaining their current cost base. Dat

In the ever-evolving realm of pharmaceutical research and development (R&D), the powerful wave of digitalization is restructuring conventional methodologies and paving the way for a novel era of ingenuity and streamlined processes. Termed digital transformation, this profound shift entails the strategic infusion of cutting-edge information technologies into established drug discovery and development procedures. Leading this revolution are technologies like big data analytics, artificial intelligence (AI), blockchain, and telemedicine. Digital transformation signifies a potential revolution in

The drug business has various strange qualities that make it very different from individuals' thought process of as industry. Its additionally an industry packed with logical inconsistencies; for instance, notwithstanding the undisputed reality that for more than a century the business has made a major contribution to human prosperity and the decrease of chronic sickness and suffering, it is still routinely recognized bygeneral society in assessment reviews as one of the most un-confided in ventures, frequently being contrasted horribly with the atomic business. It is without a doubt perhaps

More than one billion people are impacted by chronic and acute lung diseases globally Infact, non-communicable diseases, such as chronic respiratory diseases are among the biggest reasons for fatality (WHO). Despite the growing health and wellness centricity across countries, respiratory conditions have not received the attention they need. If at all they do then it’s more for infectious conditions like Tuberculosis. But when wellness is looked at holistically, healthy lungs and lung health is paramount for overall health and wellbeing. According to WHO, respiratory illnesses lead to over 10p

The creation of smart nanocarrier-based drug delivery systems, also known as Smart Drug Delivery Systems(SDDSs), was prompted by the nonspecific dispersion and unpredictable release of pharmaceuticals in Conventional Drug Delivery Systems (CDDSs). To lessen the adverse consequences associated with CDDSs, SDDSs can deliver medications to target locations with lower dose frequency and in a spatially controlled way. Chemotherapy is commonly used to treat cancer, the world's second most common cause of death. The SDDSs have sparked a lot of attention as a potential alternative to chemotherapy bec

Nutraceuticals are the supplements that help to prevent disease and maintain the normal body function. Nutraceuticals are gaining popularity due to their nutritional and medicinal effect. The worldwide nutraceutical market is valued US$117 billion, according to estimates. Herbal nutraceuticals support in maintenance of good health and the increase the health life. Nutraceuticals have shown promising outcomes in the treatment of cancer, neurological diseases, cardiovascular diseases, and other ailments. The purpose of this article is to provide knowledge about nutraceuticals and their applicat

In our constantly changing world, healthcare is an essential element of growth. Pursuing safer, more effective healthcare solutions has led to innovative strategies transforming the industry.

Clinical trials and Contract Research Organisations (CROs) play essential roles in these transformative methods. Let's explore these approaches and understand how they contribute to making healthcare safer and more effective.

Technological advancements, evolving patient expectations, and the need for proven, evidence-based therapies collectively drive substantial changes in the healthcare sector. T

CIS are syringe-like cell-puncturing machines. Bacteria deploy it for various natural functions including cell-cell communications, defence, and in endosymbionts to interact with the hosts. CIS translocate effectors molecules (toxins or proteins) into the target cell by puncturing its cell membrane. Within the target cell, effectors modulate cell components such as cytoskeleton and DNA.

CIS can be assembled on the cytoplasmic membrane and act as contact dependent system, known as Type VI secretion systems (T6SS). It can exist as free complexes in the cytoplasm, and is released into the ext

Dementia is the first sign of neuronal impairment related to Alzheimer’s disease (AD). The neurodegeneration initially appears in the hippocampus and cortex which comprises memory developing area of the brain and then spreads to additional areas of the brain causing significant shrinkage of the brain. Due to this abnormality accumulation of amyloid β plaques and tau tangles occurs consequently leading to disruption of the functioning of healthy neurons and loss of synaptic connections. Donepezil, memantine, rivastigmine, galantamine, and their combinations are primarily used for the treatment

Certainly, we are all alike, but we are all unique. And the notion that medication would be used in a way that overlooks those disparities is as absurd as walking to a sneaker store to pick up any old pair of sneakers without first verifying the size. Personalized medicine provides an excellent chance to transform a "one size fits all" strategy to diagnostics, pharmacological therapy, and treatment into a personalised strategy. Nanotechnology advancements have enabled the development of nanomaterials devices for the enhanced diagnosis and tailored treatment of a various range of complicated d

The global AI in the pharma market expanded to a size of nearly $699.3 million in 2020. The market is anticipated to increase at a rate of 32.9 %, from $699.3 million in 2020 to $ 2,895.5 million in 2025. Researchers claim that the application of these technologies enhances decision-making, maximizes creativity, increases the effectiveness of research and clinical trials, and produces new tools that benefit doctors, patients and regulators.Computer-aided drug designs have recently supplanted more traditional methods of medication development. A lot of AI is being applied to advance drug desig

Globally, cancer has been referred to as one of the most debilitating diseases. The current treatment regimenfor the treatment of the same is limited to surgical, radiation, and chemotherapeutic interventions. However, these methods have a high risk of damage to healthy tissues, while not even conferring complete cancer eradication. With the advent of nanotechnology, the treatment landscape for cancer is projected to change. While these Nano particulate modalities are highly efficacious, they pose their set of caveats. Recent studies have corroborated the enormous potential of Plant-derived e

In this editorial, we explore the remarkable potential of artificial intelligence (AI) and machine learning (ML) in revolutionizing the field of drug design. Traditional drug discovery pipelines have long been plagued by high costs, lengthy timelines, and low success rates. However, with the advent of AI and ML, a new era of accelerated and improved drug design is on the horizon. This editorial highlight the various applications of AI and ML in drug design, including target identification, virtual screening, de novo design, synthesis prediction, and clinical trial optimization. We also addres

Quantum computing is a field that uses quantum mechanics to solve complex problems faster than classical computers. It emerged in the 1980s when it was discovered that certain computational problems could be tackled more efficiently with quantum algorithms than with their classical counterparts. Unlike classical computers that use bits, which can only be 1 or 0, quantum computing involves qubits that can exist in a multidimensional state. The power of quantum computers grows exponentially with more qubits, while classical computers that add more bits can increase power only linearly. Quantum